C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉ · 9111.30 g/mol

IGF-1 LR3

IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor 1) is a modified analogue of insulin-like growth factor 1 with two changes: an arginine substitution at position 3 (which reduces binding to IGF-binding proteins) and a 13-amino-acid N-terminal extension. These modifications produce a significantly longer half-life (~20-30 hours vs ~10 minutes for native IGF-1) and increased systemic bioavailability in research models. Studied extensively for anabolic, muscle-cell proliferation, and metabolic effects.